An improved liquid chromatography–tandem mass spectrometry method for the quantification of 4-aminobiphenyl DNA adducts in urinary bladder cells and tissues

Exposure to 4-aminobiphenyl (4-ABP), an environmental and tobacco smoke carcinogen that targets the bladder urothelium, leads to DNA adduct formation and cancer development [1]. Two major analytical challenges in DNA adduct analysis of human samples have been limited sample availability and the need...

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Hlavní autoři: Randall, Kristen L., Argoti, Dayana, Paonessa, Joseph D., Ding, Yi, Oaks, Zachary, Zhang, Yuesheng, Vouros, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665277/
https://ncbi.nlm.nih.gov/pubmed/19932483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2009.11.006
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