Exacerbated Airway Toxicity of Environmental Oxidant Ozone in Mice Deficient in Nrf2

Ozone (O(3)) is a strong oxidant in air pollution that has harmful effects on airways and exacerbates respiratory disorders. The transcription factor Nrf2 protects airways from oxidative stress through antioxidant response element-bearing defense gene induction. The present study was designed to det...

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Bibliographic Details
Main Authors: Cho, Hye-Youn, Gladwell, Wesley, Yamamoto, Masayuki, Kleeberger, Steven R.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665255/
https://ncbi.nlm.nih.gov/pubmed/23766849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/254069
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