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The Molecular Basis of NOD2 Susceptibility Mutations in Crohn's Disease
Nod2 is a member of the NLR family of proteins that initiate inflammatory responses when exposed to ligands derived from bacterial components that gain access to the intra-cellular milieu. It is thus somewhat paradoxical that polymorphisms in the gene that encode NOD2 (CARD15) that lead to impaired...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3665012/ https://ncbi.nlm.nih.gov/pubmed/19079230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2008.42 |
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