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Dysregulation of mTOR Signaling in Fragile X Syndrome
Fragile X syndrome, the most common form of inherited mental retardation and leading genetic cause of autism, is caused by transcriptional silencing of the Fmr1 gene. The fragile X mental retardation protein (FMRP), the gene product of Fmr1, is an RNA binding protein that negatively regulates transl...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3665010/ https://ncbi.nlm.nih.gov/pubmed/20071534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3696-09.2010 |
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