Skin Stem Cell Hypotheses and Long Term Clone Survival – Explored Using Agent-based Modelling

Epithelial renewal in skin is achieved by the constant turnover and differentiation of keratinocytes. Three popular hypotheses have been proposed to explain basal keratinocyte regeneration and epidermal homeostasis: 1) asymmetric division (stem-transit amplifying cell); 2) populational asymmetry (pr...

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Détails bibliographiques
Auteurs principaux: Li, X., Upadhyay, A. K., Bullock, A. J., Dicolandrea, T., Xu, J., Binder, R. L., Robinson, M. K., Finlay, D. R., Mills, K. J., Bascom, C. C., Kelling, C. K., Isfort, R. J., Haycock, J. W., MacNeil, S., Smallwood, R. H.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664904/
https://ncbi.nlm.nih.gov/pubmed/23712735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01904
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