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Exploring Hypotheses of the Actions of TGF-β1 in Epidermal Wound Healing Using a 3D Computational Multiscale Model of the Human Epidermis

In vivo and in vitro studies give a paradoxical picture of the actions of the key regulatory factor TGF-β1 in epidermal wound healing with it stimulating migration of keratinocytes but also inhibiting their proliferation. To try to reconcile these into an easily visualized 3D model of wound healing...

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Detalhes bibliográficos
Main Authors: Sun, Tao, Adra, Salem, Smallwood, Rod, Holcombe, Mike, MacNeil, Sheila
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796169/
https://ncbi.nlm.nih.gov/pubmed/20046881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008515
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