Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets

BACKGROUND: Genome-wide association studies (GWAS) have recently identified many new genetic variants associated with the development of type 2 diabetes. Many of these variants are in introns of known genes or between known genes, suggesting they affect the expression of these genes. The regulation...

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Hlavní autoři: Ho, Maggie M, Yoganathan, Piriya, Chu, Kwan Yi, Karunakaran, Subashini, Johnson, James D, Clee, Susanne M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664586/
https://ncbi.nlm.nih.gov/pubmed/23442068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-14-10
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