GIP-Overexpressing Mice Demonstrate Reduced Diet-Induced Obesity and Steatosis, and Improved Glucose Homeostasis

Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone that potentiates glucose-stimulated insulin secretion during a meal. Since GIP has also been shown to exert β-cell prosurvival and adipocyte lipogenic effects in rodents, both GIP receptor agonists and antagonists have...

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Main Authors: Kim, Su-Jin, Nian, Cuilan, Karunakaran, Subashini, Clee, Susanne M., Isales, Carlos M., McIntosh, Christopher H. S.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388996/
https://ncbi.nlm.nih.gov/pubmed/22802954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040156
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