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Short-term High-Dose Effect of Lovastatin on Thrombolysis by rt-PA in a Human Whole-Blood in vitro Clot Model

High-dose hydroxymethylglutaryl coenzyme. A reductase inhibitor (statin) administration reduces neuronal injury and improves outcomes in experimental models of acute ischemic stroke, and has been shown to be safe in a phase 1 dose-escalation study using lovastatin at doses higher than currently appr...

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Detalhes bibliográficos
Principais autores: Kandadai, Madhuvanthi A., Meunier, Jason, Lindsell, Christopher J., Shaw, George J., Elkind, Mitchell S. V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664397/
https://ncbi.nlm.nih.gov/pubmed/22621227
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