The human porphyrin transporter ABCB6 is dispensable for erythropoiesis but responsible for the new blood group system Langereis

The human ATP-binding cassette (ABC) transporter ABCB6 has been described as a mitochondrial porphyrin transporter essential for heme biosynthesis(1), but is also suspected to contribute to anticancer drug resistance(2–4), as do other ABC transporters located at the plasma membrane. We identified AB...

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Hauptverfasser: Helias, Virginie, Saison, Carole, Ballif, Bryan A., Peyrard, Thierry, Takahashi, Junko, Takahashi, Hideo, Tanaka, Mitsunobu, Deybach, Jean-Charles, Puy, Hervé, Le Gall, Maude, Sureau, Camille, Pham, Bach-Nga, Le Pennec, Pierre-Yves, Tani, Yoshihiko, Cartron, Jean-Pierre, Arnaud, Lionel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664204/
https://ncbi.nlm.nih.gov/pubmed/22246506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.1069
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