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Dose- and time-dependent effect of high glucose concentration on viability of notochordal cells and expression of matrix degrading and fibrotic enzymes

PURPOSE: Diabetes mellitus is an important aetiological factor in intervertebral disc degeneration. The disappearance of notochordal cells in the nucleus pulposus is thought to be the starting point for intervertebral disc degeneration. A cellular effect of diabetes mellitus on apoptosis of notochor...

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Detalhes bibliográficos
Main Authors: Park, Eun-Young, Park, Jong-Beon
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664153/
https://ncbi.nlm.nih.gov/pubmed/23503638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00264-013-1836-2
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