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High glucose-induced oxidative stress promotes autophagy through mitochondrial damage in rat notochordal cells
PURPOSE: Diabetes mellitus is associated with an increased risk of intervertebral disc degeneration (IDD). Reactive oxygen species (ROS), oxidative stressors, play a key role in autophagy of diabetes-associated diseases. Mitochondria are known to be the main source of endogenous ROS in most mammalia...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3843215/ https://ncbi.nlm.nih.gov/pubmed/23907350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00264-013-2037-8 |
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