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Activation of c-kit in dendritic cells regulates T helper cell differentiation and allergic asthma

Dendritic cells (DCs) are integral to differentiation of T helper cells into Th1, Th2 and Th17 subsets. Interleukin-6 (IL-6) plays an important role in regulating these three arms of the immune response by limiting a Th1 response and promoting Th2 and Th17 responses. In this study, we investigated p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Krishnamoorthy, Nandini, Oriss, Timothy B., Paglia, Melissa, Fei, Mingjian, Yarlagadda, Manohar, Vanhaesebroeck, Bart, Ray, Anuradha, Ray, Prabir
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664066/
https://ncbi.nlm.nih.gov/pubmed/18454155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1766
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