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Enantioselective Synthesis of (E)-δ-Silyl-anti-Homoallylic Alcohols Via An Enantiodivergent Hydroboration-Crotylboration Reaction of a Racemic Allenylsilane

[Image: see text] The enantioselective hydroboration of racemic allenylsilane (±)-4 with ((d)Ipc)(2)BH proceeds via enantiodivergent pathways to give vinylborane 11 and crotylborane intermediate (S)-E-5. Subsequent crotylboration of aldehyde substrates with (S)-E-5 at −78 °C provides (E)-δ-silyl-ant...

詳細記述

保存先:
書誌詳細
主要な著者: Chen, Ming, Roush, William R.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663895/
https://ncbi.nlm.nih.gov/pubmed/23534391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol4004405
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