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Enantioselective Syntheses of syn- and anti-β-Hydroxyallylsilanes Via Allene Hydroboration-Aldehyde Allylboration Reactions

[Image: see text] The kinetic hydroboration of allenylsilane 5 with ((d)Ipc)(2)BH at −40 °C provides allylborane 9Z with ≥12:1 selectivity. When the hydroboration is performed at temperatures above −40 °C, 9Z isomerizes to the thermodynamically more stable allylborane 9E with >20:1 selectivity. S...

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Bibliographic Details
Main Authors: Chen, Ming, Roush, William R.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075570/
https://ncbi.nlm.nih.gov/pubmed/21410173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol200392u
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