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A Phase 1 Study of Heat/Phenol Killed, E. coli-Encapsulated, Recombinant Modified Peanut Proteins Ara h 1, Ara h 2, and Ara h 3 (EMP-123) for the Treatment of Peanut Allergy

BACKGROUND: Immunotherapy for peanut allergy may be limited by the risk of adverse reactions. OBJECTIVE: To investigate the safety and immunologic effects of a vaccine containing modified peanut proteins. METHODS: This was a Phase 1 trial of EMP-123, a rectally administered suspension of recombinant...

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Autori principali: Wood, Robert A., Sicherer, Scott H., Burks, A. Wesley, Grishin, Alexander, Henning, Alice K., Lindblad, Robert, Stablein, Donald, Sampson, Hugh A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663889/
https://ncbi.nlm.nih.gov/pubmed/23621498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.12158
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