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Sin1 regulates Treg development but is not required for T cell growth and proliferation

Mammalian Sin1 plays key roles in the regulation of mitogen activated protein kinase (MAPK) and mammalian target of rapamycin (mTOR) signaling. Sin1 is an essential component of mTOR complex (mTORC) 2. The function of Sin1 and mTORC2 remains largely unknown in T cells. Here we investigate Sin1 funct...

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Bibliografische gegevens
Hoofdauteurs: Chang, Xing, Lazorchak, Adam S., Liu, Dou, Su, Bing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663871/
https://ncbi.nlm.nih.gov/pubmed/22678916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142066
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