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Sin1 regulates Treg development but is not required for T cell growth and proliferation
Mammalian Sin1 plays key roles in the regulation of mitogen activated protein kinase (MAPK) and mammalian target of rapamycin (mTOR) signaling. Sin1 is an essential component of mTOR complex (mTORC) 2. The function of Sin1 and mTORC2 remains largely unknown in T cells. Here we investigate Sin1 funct...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3663871/ https://ncbi.nlm.nih.gov/pubmed/22678916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142066 |
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