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Model Selection Approach Suggests Causal Association between 25-Hydroxyvitamin D and Colorectal Cancer

INTRODUCTION: Vitamin D deficiency has been associated with increased risk of colorectal cancer (CRC), but causal relationship has not yet been confirmed. We investigate the direction of causation between vitamin D and CRC by extending the conventional approaches to allow pleiotropic relationships a...

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Autors principals: Zgaga, Lina, Agakov, Felix, Theodoratou, Evropi, Farrington, Susan M., Tenesa, Albert, Dunlop, Malcolm G., McKeigue, Paul, Campbell, Harry
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663843/
https://ncbi.nlm.nih.gov/pubmed/23717431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063475
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