Rotavirus Enterotoxin NSP4 Has Mucosal Adjuvant Properties

Rotavirus nonstructural protein 4 (NSP4) is a protein with pleiotropic properties. It functions in rotavirus morphogenesis, pathogenesis, and is the first described viral enterotoxin. Since many bacterial toxins function as potent mucosal adjuvants, we evaluated whether baculovirus-expressed recombi...

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Autores principales: Kavanagh, Owen V., Ajami, Nadim J., Cheng, Elly, Ciarlet, Max, Guerrero, Roberto A., Zeng, Carl Q.-Y., Crawford, Sue E., Estes, Mary K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663485/
https://ncbi.nlm.nih.gov/pubmed/20197138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.02.063
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