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Profile of perampanel and its potential in the treatment of partial onset seizures
Perampanel (PER) is a novel antiepileptic compound that decreases neuronal excitability by modulating glutamatergic transmission through selective noncompetitive blockade of AMPA receptors. PER has been evaluated in three pivotal placebo-controlled randomized trials as adjunctive therapy in adult dr...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3663472/ https://ncbi.nlm.nih.gov/pubmed/23717043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S30129 |
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