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Clinical Neuropathology Practice News 2-2013: immunohistochemistry pins IDH in glioma – molecular testing procedures under scrutiny

Isocitrate dehydrogenase 1 (IDH1) gene mutations occur in ~ 60 – 90% of diffuse and anaplastic gliomas and secondary glioblastomas. IDH status is strongly associated with patient survival times and IDH testing is relevant for clinical patient management and for stratification in clinical trials. A r...

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Bibliographic Details
Main Authors: Preusser, Matthias, van den Bent, Martin
Format: Artigo
Language:Inglês
Published: Dustri-Verlag Dr. Karl Feistle 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663465/
https://ncbi.nlm.nih.gov/pubmed/23442355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5414/NP300622
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