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Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia
We report preclinical proof of principle for effective treatment of B-precursor acute lymphoblastic leukemia (ALL) by targeting the spleen tyrosine kinase (SYK)–dependent antiapoptotic blast cell survival machinery with a unique nanoscale pharmaceutical composition. This nanoscale liposomal formulat...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3663427/ https://ncbi.nlm.nih.gov/pubmed/23568490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-470633 |
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