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ω-Conotoxins GVIA, MVIIA and CVID: SAR and Clinical Potential

Highly selective N-type voltage-gated calcium (Ca(V)) channel inhibitors from cone snail venom (the ω-conotoxins) have emerged as a new class of therapeutics for the treatment of chronic and neuropathic pain. Earlier in 2005, Prialt (Elan) or synthetic ω-conotoxin MVIIA, was the first ω-conotoxin to...

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Autori principali: Schroeder, Christina I., Lewis, Richard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Diversity Preservation International (MDPI) 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663408/
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