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Effects of Lissoclibadins and Lissoclinotoxins, Isolated from a Tropical Ascidian Lissoclinum cf. badium, on IL-8 production in a PMA-stimulated Promyelocytic Leukemia Cell Line

The effects of seven compounds 1–7, isolated from a tropical ascidian Lissoclinum cf. badium, on IL-8 production in PMA-stimulated HL-60 cells were examined. Lissoclibadins 2 (2) and 3 (3) and lissoclinotoxin F (5) increased the IL-8 production in a dose-dependent manner. Compounds 2 and 5 are struc...

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Detalhes bibliográficos
Main Authors: Oda, Taiko, Fujiwara, Takeshi, Liu, Hongwei, Ukai, Kazuyo, Mangindaan, Remy E. P., Mochizuki, Masataka, Namikoshi, Michio
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663407/
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