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Effects of bistheonellide A, an Actin-polymerization Inhibitor, on Chinese Hamster V79 Cells and on IL-8 Production in PMA-stimulated HL-60 Cells

Bioassay-guided isolation from the ethanol extract of a marine sponge Theonella sp. collected in Palau yielded bistheonellide A, which strongly inhibited the colony formation of Chinese hamster V79 cells (EC(50) = 6.8 nM). Bistheonellide A is an actin-polymerization inhibitor and was suggested to co...

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Detalhes bibliográficos
Main Authors: Oda, Taiko, Xu, Jinzhong, Fujita, Ayako, Mochizuki, Masataka, Namikoshi, Michio
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663404/
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