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Inhibition of constitutive aryl hydrocarbon receptor (AhR) signaling attenuates androgen independent signaling and growth in (C4-2) prostate cancer cells

The aryl hydrocarbon receptor is a member of the basic-helix-loop-helix family of transcription factors. AhR mediates the biochemical and toxic effects of a number of polyaromatic hydrocarbons such as 2,3,7,8,-tetrachloro-dibenzo-p-dioxin (TCDD). AhR is widely known for regulating the transcription...

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Autores principales: Tran, Cindy, Richmond, Oliver, Aaron, LaTayia, Powell, Joann B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663294/
https://ncbi.nlm.nih.gov/pubmed/23266674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.12.010
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