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KRAS and BRAF Mutation Analysis in Colorectal Adenocarcinoma Specimens with a Low Percentage of Tumor Cells

BACKGROUND AND OBJECTIVE: The rapid development of molecular biology techniques allows for the introduction of real-time polymerase chain reaction (PCR) methods with a limit of mutation detection at 1 % in a background of wild-type DNA. Analysis of KRAS mutations in codons 12, 13, and 61, together w...

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Bibliografische gegevens
Hoofdauteurs: Lewandowska, Marzena Anna, Jóźwicki, Wojciech, Żurawski, Bogdan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing AG 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663254/
https://ncbi.nlm.nih.gov/pubmed/23606169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40291-013-0025-8
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