HSP70I IS A CRITICAL COMPONENT OF THE IMMUNE RESPONSE LEADING TO VITILIGO

HSP70i and other stress proteins have been used in anti-tumor vaccines. This begs the question whether HSP70i plays a unique role in immune activation. We vaccinated inducible HSP70i (Hsp70-1) knockout mice and wild-type animals with optimized TRP-1, a highly immunogenic melanosomal target molecule....

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Hauptverfasser: Mosenson, Jeffrey A., Zloza, Andrew, Klarquist, Jared, Barfuss, Allison J., Guevara-Patino, Jose A., Le Poole, I. Caroline
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662798/
https://ncbi.nlm.nih.gov/pubmed/21978301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2011.00916.x
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