Hydrogen Sulfide Donor NaHS Reduces Organ Injury in a Rat Model of Pneumococcal Pneumosepsis, Associated with Improved Bio-Energetic Status

Sepsis is characterized by a generalized inflammatory response and organ failure, associated with mitochondrial dysfunction. Hydrogen sulfide donor NaHS has anti-inflammatory properties, is able to reduce metabolism and can preserve mitochondrial morphology and function. Rats were challenged with li...

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Hauptverfasser: Aslami, Hamid, Pulskens, Wilco P., Kuipers, Maria T., Bos, Aafkeline P., van Kuilenburg, André B. P., Wanders, Ronald J. A., Roelofsen, Jeroen, Roelofs, Joris J. T. H., Kerindongo, Raphaela P., Beurskens, Charlotte J. P., Schultz, Marcus J., Kulik, Wim, Weber, Nina C., Juffermans, Nicole P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662774/
https://ncbi.nlm.nih.gov/pubmed/23717435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063497
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