Hydrogen Sulfide Donor NaHS Reduces Organ Injury in a Rat Model of Pneumococcal Pneumosepsis, Associated with Improved Bio-Energetic Status

Sepsis is characterized by a generalized inflammatory response and organ failure, associated with mitochondrial dysfunction. Hydrogen sulfide donor NaHS has anti-inflammatory properties, is able to reduce metabolism and can preserve mitochondrial morphology and function. Rats were challenged with li...

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Main Authors: Aslami, Hamid, Pulskens, Wilco P., Kuipers, Maria T., Bos, Aafkeline P., van Kuilenburg, André B. P., Wanders, Ronald J. A., Roelofsen, Jeroen, Roelofs, Joris J. T. H., Kerindongo, Raphaela P., Beurskens, Charlotte J. P., Schultz, Marcus J., Kulik, Wim, Weber, Nina C., Juffermans, Nicole P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662774/
https://ncbi.nlm.nih.gov/pubmed/23717435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063497
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