Microbial Translocation Is Associated with Extensive Immune Activation in Dengue Virus Infected Patients with Severe Disease

BACKGROUND: Severe dengue virus (DENV) disease is associated with extensive immune activation, characterized by a cytokine storm. Previously, elevated lipopolysaccharide (LPS) levels in dengue were found to correlate with clinical disease severity. In the present cross-sectional study we identified...

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Bibliografski detalji
Glavni autori: van de Weg, Cornelia A. M., Pannuti, Cláudio S., de Araújo, Evaldo S. A., van den Ham, Henk-Jan, Andeweg, Arno C., Boas, Lucy S. V., Felix, Alvina C., Carvalho, Karina I., de Matos, Andreia M., Levi, José E., Romano, Camila M., Centrone, Cristiane C., de Lima Rodrigues, Celia L., Luna, Expedito, van Gorp, Eric C. M., Osterhaus, Albert D. M. E., Martina, Byron E. E., Kallas, Esper G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662706/
https://ncbi.nlm.nih.gov/pubmed/23717702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002236
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