Mitochondrial Genetic Background Modifies the Relationship between Traffic-Related Air Pollution Exposure and Systemic Biomarkers of Inflammation

BACKGROUND: Mitochondria are the main source of reactive oxygen species (ROS). Human mitochondrial haplogroups are linked to differences in ROS production and oxidative-stress induced inflammation that may influence disease pathogenesis, including coronary artery disease (CAD). We previously showed...

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Main Authors: Wittkopp, Sharine, Staimer, Norbert, Tjoa, Thomas, Gillen, Daniel, Daher, Nancy, Shafer, Martin, Schauer, James J., Sioutas, Constantinos, Delfino, Ralph J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662686/
https://ncbi.nlm.nih.gov/pubmed/23717615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064444
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