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Mitochondrial genetic background modifies the relationship between traffic-related air pollution exposure and systemic biomarkers of inflammation.

Mitochondria are the main source of reactive oxygen species (ROS). Human mitochondrial haplogroups are linked to differences in ROS production and oxidative-stress induced inflammation that may influence disease pathogenesis, including coronary artery disease (CAD). We previously showed that traffic...

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Detalhes bibliográficos
Main Authors: Sharine Wittkopp, Norbert Staimer, Thomas Tjoa, Daniel Gillen, Nancy Daher, Martin Shafer, James J Schauer, Constantinos Sioutas, Ralph J Delfino
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3662686?pdf=render
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