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Cell-Autonomous Function of Runx1 Transcriptionally Regulates Mouse Megakaryocytic Maturation
RUNX1 transcription factor (TF) is a key regulator of megakaryocytic development and when mutated is associated with familial platelet disorder and predisposition to acute myeloid leukemia (FPD-AML). We used mice lacking Runx1 specifically in megakaryocytes (MK) to characterized Runx1-mediated trans...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3662678/ https://ncbi.nlm.nih.gov/pubmed/23717578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064248 |
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