Cell-Autonomous Function of Runx1 Transcriptionally Regulates Mouse Megakaryocytic Maturation

RUNX1 transcription factor (TF) is a key regulator of megakaryocytic development and when mutated is associated with familial platelet disorder and predisposition to acute myeloid leukemia (FPD-AML). We used mice lacking Runx1 specifically in megakaryocytes (MK) to characterized Runx1-mediated trans...

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Bibliografske podrobnosti
Main Authors: Pencovich, Niv, Jaschek, Ram, Dicken, Joseph, Amit, Ayelet, Lotem, Joseph, Tanay, Amos, Groner, Yoram
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662678/
https://ncbi.nlm.nih.gov/pubmed/23717578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064248
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