Chargement en cours...
Inhibition of redox/Fyn/c-Cbl pathway function by Cdc42 controls tumour initiation capacity and tamoxifen sensitivity in basal-like breast cancer cells
We found that basal-like breast cancer (BLBC) cells use Cdc42 to inhibit function of the redox/Fyn/c-Cbl (RFC) pathway, which normally functions to convert small increases in oxidative status into enhanced degradation of c-Cbl target proteins. Restoration of RFC pathway function by genetic or pharma...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
WILEY-VCH Verlag
2013
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3662315/ https://ncbi.nlm.nih.gov/pubmed/23606532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201202140 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|