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Brainstem facilitations and descending serotonergic controls contribute to visceral nociception but not pregabalin analgesia in rats

Pro-nociceptive ON-cells in the rostral ventromedial medulla (RVM) facilitate nociceptive processing and contribute to descending serotonergic controls. We use RVM injections of neurotoxic dermorphin-saporin (Derm-SAP) in rats to evaluate the role of putative ON-cells, or μ-opioid receptor-expressin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sikandar, Shafaq, Bannister, Kirsty, Dickenson, Anthony H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Scientific Publishers Ireland 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661978/
https://ncbi.nlm.nih.gov/pubmed/22579856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.05.009
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