Molecular phenotype predicts sensitivity of squamous cell carcinoma of the head and neck to epidermal growth factor receptor inhibition

Despite nearly universal expression of the wild‐type epidermal growth factor receptor (EGFR) and reproducible activity of EGFR inhibitors in patients with squamous cell carcinoma of the head and neck (SCCHN), the majority of patients will not have objective responses. The mechanisms of this intrinsi...

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Autors principals: Young, Natalie R., Liu, Jing, Pierce, Carolyn, Wei, Tai-Fen, Grushko, Tatyana, Olopade, Olufunmilayo I., Liu, Wanqing, Shen, Christine, Seiwert, Tanguy Y., Cohen, Ezra E.W.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2012
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Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661759/
https://ncbi.nlm.nih.gov/pubmed/23200321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2012.11.001
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