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APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study
Deposition of amyloid-β (Aβ) in the cerebral cortex is thought to be a pivotal event in Alzheimer’s disease (AD) pathogenesis with a significant genetic contribution. Molecular imaging can provide an early noninvasive phenotype but small samples have prohibited genome-wide association studies (GWAS)...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3661739/ https://ncbi.nlm.nih.gov/pubmed/23419831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.19 |
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