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Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments
Protein structures evolved through a complex interplay of cooperative interactions and it is still very challenging to design new protein folds de novo. Here, we present a strategy to design self-assembling polypeptide nanostructured polyhedra, based on modularization using orthogonal dimerizing seg...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3661711/ https://ncbi.nlm.nih.gov/pubmed/23624438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1248 |
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