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Disulfide mapping reveals the domain swapping as the crucial process of the structural conversion of prion protein
Prion diseases are infectious conformational diseases. Despite the determination of many native prion protein (PrP) structures and in vitro production of infectious prions from recombinant PrP the structural background of PrP conversion remains the largest unsolved problem. The aggregated state of P...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166501/ https://ncbi.nlm.nih.gov/pubmed/21555920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.2.16232 |
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