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Disulfide mapping reveals the domain swapping as the crucial process of the structural conversion of prion protein
Prion diseases are infectious conformational diseases. Despite the determination of many native prion protein (PrP) structures and in vitro production of infectious prions from recombinant PrP the structural background of PrP conversion remains the largest unsolved problem. The aggregated state of P...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166501/ https://ncbi.nlm.nih.gov/pubmed/21555920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.2.16232 |
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