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APOBEC3G-Augmented Stem Cell Therapy to Modulate HIV Replication: A Computational Study

The interplay between the innate immune system restriction factor APOBEC3G and the HIV protein Vif is a key host-retrovirus interaction. APOBEC3G can counteract HIV infection in at least two ways: by inducing lethal mutations on the viral cDNA; and by blocking steps in reverse transcription and vira...

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Detalhes bibliográficos
Main Authors: Hosseini, Iraj, Mac Gabhann, Feilim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661658/
https://ncbi.nlm.nih.gov/pubmed/23724012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063984
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