TSG-6 Produced by hMSCs Delays the Onset of Autoimmune Diabetes by Suppressing Th1 Development and Enhancing Tolerogenicity

Genetic and immunological screening for type 1 diabetes has led to the possibility of preventing disease in susceptible individuals. Here, we show that human mesenchymal stem/stromal cells (hMSCs) and tumor necrosis factor-α–stimulated gene 6 (TSG-6), a protein produced by hMSCs in response to signa...

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Bibliografiske detaljer
Main Authors: Kota, Daniel J., Wiggins, Lindsey L., Yoon, Nara, Lee, Ryang Hwa
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661629/
https://ncbi.nlm.nih.gov/pubmed/23349496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0931
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