Rac1 Signaling Is Required for Insulin-Stimulated Glucose Uptake and Is Dysregulated in Insulin-Resistant Murine and Human Skeletal Muscle

The actin cytoskeleton–regulating GTPase Rac1 is required for insulin-stimulated GLUT4 translocation in cultured muscle cells. However, involvement of Rac1 and its downstream signaling in glucose transport in insulin-sensitive and insulin-resistant mature skeletal muscle has not previously been inve...

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Detaylı Bibliyografya
Asıl Yazarlar: Sylow, Lykke, Jensen, Thomas E., Kleinert, Maximilian, Højlund, Kurt, Kiens, Bente, Wojtaszewski, Jørgen, Prats, Clara, Schjerling, Peter, Richter, Erik A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2013
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661612/
https://ncbi.nlm.nih.gov/pubmed/23423567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1148
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