Rac1 governs exercise‐stimulated glucose uptake in skeletal muscle through regulation of GLUT4 translocation in mice

KEY POINT: Exercise increases skeletal muscle energy turnover and one of the important substrates for the working muscle is glucose taken up from the blood. The GTPase Rac1 can be activated by muscle contraction and has been found to be necessary for insulin‐stimulated glucose uptake, although its r...

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Опубликовано в: :J Physiol
Главные авторы: Sylow, Lykke, Nielsen, Ida L., Kleinert, Maximilian, Møller, Lisbeth L. V., Ploug, Thorkil, Schjerling, Peter, Bilan, Philip J., Klip, Amira, Jensen, Thomas E., Richter, Erik A.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Muscle
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009787/
https://ncbi.nlm.nih.gov/pubmed/27061726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272039
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