A Longitudinal Study of Cognition, Proton MR Spectroscopy and Synaptic and Neuronal Pathology in Aging Wild-type and AβPPswe-PS1dE9 Mice

Proton magnetic resonance spectroscopy ((1)H MRS) is a valuable tool in Alzheimer’s disease research, investigating the functional integrity of the brain. The present longitudinal study set out to characterize the neurochemical profile of the hippocampus, measured by single voxel (1)H MRS at 7 Tesla...

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Detalhes bibliográficos
Main Authors: Jansen, Diane, Zerbi, Valerio, Janssen, Carola I. F., Dederen, Pieter J. W. C., Mutsaers, Martina P. C., Hafkemeijer, Anne, Janssen, Anna-Lena, Nobelen, Cindy L. M., Veltien, Andor, Asten, Jack J., Heerschap, Arend, Kiliaan, Amanda J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661598/
https://ncbi.nlm.nih.gov/pubmed/23717459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063643
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