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Pancreatic Islet Xenograft Survival in Mice Is Extended by a Combination of Alpha-1-Antitrypsin and Single-Dose Anti-CD4/CD8 Therapy

Clinical pancreatic islet transplantation is under evaluation for the treatment of autoimmune diabetes, yet several limitations preclude widespread use. For example, there is a critical shortage of human pancreas donors. Xenotransplantation may solve this problem, yet it evokes a rigorous immune res...

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Detalhes bibliográficos
Main Authors: Ashkenazi, Efrat, Baranovski, Boris M., Shahaf, Galit, Lewis, Eli C
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661573/
https://ncbi.nlm.nih.gov/pubmed/23717456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063625
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