Exploration of α1-Antitrypsin Treatment Protocol for Islet Transplantation: Dosing Plan and Route of Administration

Lifelong weekly infusions of human α1-antitrypsin (hAAT) are currently administered as augmentation therapy for patients with genetic AAT deficiency (AATD). Several recent clinical trials attempt to extend hAAT therapy to conditions outside AATD, including type 1 diabetes. Because the endpoint for A...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Baranovski, Boris M., Ozeri, Eyal, Shahaf, Galit, Ochayon, David E., Schuster, Ronen, Bahar, Nofar, Kalay, Noa, Cal, Pablo, Mizrahi, Mark I., Nisim, Omer, Strauss, Pnina, Schenker, Eran, Lewis, Eli C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Inflammation, Immunopharmacology, and Asthma
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118642/
https://ncbi.nlm.nih.gov/pubmed/27821710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.236067
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