Small Neutral Amino Acid Ester Prodrugs of Acyclovir Targeting Amino Acid Transporters on the Cornea: Possible Antiviral Agents Against Ocular HSV-1 Infections

The aim of this study was to characterize the affinity and permeability patterns of the amino acid ester prodrugs of acyclovir (ACV), L-alanine-ACV (AACV), L-serine-ACV (SACV), L-serine-succinate-ACV (SSACV) and L-cysteine-ACV (CACV) on rabbit primary corneal epithelial cell culture (rPCEC) and on r...

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Hlavní autoři: Suresh, Katragadda, Xiadong, Zhu, Ravi, Talluri S., Mitra, Ashim K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Libertas Academica 2010
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661498/
https://ncbi.nlm.nih.gov/pubmed/23861613
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